The API 4000 LC/MS/MS System delivers high-performance quantitation and identification across a wide range of LC flow rates. It uses the Turbo V™ ion source to produce ions from liquid samples and allows all modes of MS/MS operation for full characterization of biopharmaceutical compounds and the specificity needed for new drug development. For pharmaceutical and pharmakinetic samples, MS/MS has the sensitivity and specificity required to analyze hundreds of samples per day without extensive sample preparation. For peptides and proteins, molecular weights can be determined with accuracies better than 0.01% at 200 kDa.
It has the following features:
- The standard Turbo V™ ion source provides a plug-and-play TurboIonSpray® probe, APCI probe and APPI probe, a durable ceramic interface, and compatibility with high flow rates.
- LINAC® collision cell eliminates cross-talk and allows for multi-component analysis during an LC run.
- Rugged Curtain Gas™ interface technology combined with improved gas dynamics reduces maintenance and increases uptime.
- Scanning in a mass range of m/z 5–3000, sensitivity ppb-ppt